Cannabis XVIII: Isolation and synthesis of olivetol derivatives formed in the pyrolysis of cannabidiol

Autor:	Cornelis A. Salemink, J. M. Luteyn, H. J. W. Spronck
Rok vydání:	1978
Předmět:	chemistry.chemical_compound Chemistry Reagent medicine Organic chemistry General Chemistry Olivetol Cannabidiol Pyrolysis medicine.drug
Zdroj:	Recueil des Travaux Chimiques des Pays-Bas. 97:187-190
ISSN:	0165-0513
DOI:	10.1002/recl.19780970704
Popis:	Pyrolysis of cannabidiol results in the formation of several new cannabinoids and cracking products. In an earlier paper several structures were proposed for the cracking products based on GCMS measurements. In this paper the isolation and synthesis of the majority of these cracking products - which are in general C(2)-substituted olivetol derivatives - is described. 2,6-Dimethoxy-4-pentylphenyl-lithium and the cuprates derived therefrom proved to be very promising intermediates for the synthesis of olivetol derivatives specifically substituted at C(2). The versatility of these reagents is illustrated by several examples.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e914c4420b0b087a346e955418ce4c8c https://doi.org/10.1002/recl.19780970704 Zobrazit plný text záznamu Plný text