Autor:	Kuddusi Cengiz, R. Amanvermez, I. Gören
Rok vydání:	1999
Předmět:	Nephrology medicine.medical_specialty Creatinine Vascular smooth muscle business.industry Urology medicine.medical_treatment Renal function Vasodilation Endothelin 1 Nitric oxide chemistry.chemical_compound Endocrinology chemistry Internal medicine medicine business Dialysis
Zdroj:	International Urology and Nephrology. 31:845-850
ISSN:	0301-1623
Popis:	Nitric oxide (NO) and endothelin-1 (ET-1) are two substances that take part in the regulation of vascular smooth muscle tone. ET-1 is a vasoconstrictor peptide and NO is a vasodilating molecule. There have been contradictory reports of the plasma levels of these substances in patients with chronic renal failure (CRF). We studied plasma levels of ET-1 and NO in hypertensive and normotensive patients with CRF either on dialysis or on non-dialysis treatment. A total of 41 patients were studied, 23 males and 18 females with mean age of 50.39±14.46 years. The control group consisted of healthy subjects (22 males and 8 females) with a mean age of 46.50±8.21 years. The plasma levels of ET-1 were significantly higher and NO levels were lower in the CRF patients than in controls (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e912a8a4ae6faf5ccdbda9625d0c5e4c https://doi.org/10.1023/a:1007170218824 Zobrazit plný text záznamu Full text from SpringerLink