A One-Pot Method for the Synthesis of Naphthyridines via Modified Friedländer Reaction

Autor:	Pavel Zhichkin, David J. Fairfax, W. Martin Rennells, Catherine M. Beer
Rok vydání:	2006
Předmět:	Chemistry Organic Chemistry Directed ortho metalation Combinatorial chemistry
Zdroj:	Synlett. 2006:0379-0382
ISSN:	1437-2096 0936-5214
Popis:	A one-pot method for the preparation of 1,8-naphthyridine derivatives is reported. The method involves the dimetalation of an appropriate N-2-pyridylpivalamide or tert-butylcarbamate followed by reaction with a β-dimethylamino or β-alkoxyacrolein derivative. This method is also applicable to 1,6-naphthyridines.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e90e4d67ea6654bb8c573090aa60dd32 https://doi.org/10.1055/s-2006-926229 Zobrazit plný text záznamu