Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice

Autor: Erik B. Faber, Nan Wang, Kristen John, Luxin Sun, Henry L. Wong, David Burban, Rawle Francis, Defeng Tian, Kwon H. Hong, An Yang, Liming Wang, Mazen Elsaid, Hira Khalid, Nicholas M. Levinson, Ernst Schönbrunn, Jon E. Hawkinson, Gunda I. Georg
Rok vydání: 2023
Předmět:
Zdroj: Journal of Medicinal Chemistry. 66:1928-1940
ISSN: 1520-4804
0022-2623
DOI: 10.1021/acs.jmedchem.2c01731
Databáze: OpenAIRE