REACTIONS OF RABBITS TO NON-HEMOLYTIC STREPTOCOCCI: III. A STUDY OF MODES OF SENSITIZATION

Autor:	Charles H. Hitchcock, Homer F. Swift, Clifford L. Derick
Rok vydání:	1930
Předmět:	Allergy medicine.anatomical_structure Streptococcus business.industry Immunology medicine Immunology and Allergy medicine.disease medicine.disease_cause business Sensitization
Zdroj:	Journal of Experimental Medicine. 52:1-22
ISSN:	1540-9538 0022-1007
Popis:	The most satisfactory method thus far found for the induction and maintenance of a high degree of hypersensitiveness—"allergy," "hyperergy"—against non-hemolytic streptococci consists in the repeated production of small focal lesions with minimal doses of bacteria. After a preliminary sensitizing period of about 2 weeks' duration with either large initial, or small multiple daily inoculations, the later foci need be produced only at 7 to 10 day intervals. Chronicity of low-grade infection appears to be an important factor in the attainment of a high degree of hypersensitiveness.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e8db42d8c9edde949e78ad503ed92cb2 https://doi.org/10.1084/jem.52.1.1 Zobrazit plný text záznamu