Enamine-mediated Mannich reaction of cyclic N,O-acetals and amido acetals: the multigram synthesis of pyrrolidine alkaloid precursors

Autor:	Rakhymzhan A. Turmanov, Andrey V. Smolobochkin, Almir S. Gazizov, Tanzilya S. Rizbayeva, Danil D. Zapylkin, Julia K. Voronina, Alexandra D. Voloshina, Victor V. Syakaev, Alexey V. Kurenkov, Alexander R. Burilov, Michail A. Pudovik
Rok vydání:	2022
Předmět:	Organic Chemistry Physical and Theoretical Chemistry Biochemistry
Zdroj:	Organic & Biomolecular Chemistry. 20:7105-7111
ISSN:	1477-0539 1477-0520
Popis:	An l-proline/Brønsted acid/base organocatalytic system enables gram-scale synthesis of 2-(acylmethylene)pyrrolidines through enamine activation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e8d0173cbc25c2ec072c3c2b37c95bc8 https://doi.org/10.1039/d2ob01276f Zobrazit plný text záznamu