Evidence-Based Guidelines for the Treatment of Helicobacter pylori Infection in Korea: 2020 Revised Edition
| Autor: | 박재명 ( Jae Myung Park ), 신철민 ( Cheol Min Shin ), 최미영 ( Miyoung Choi ), 김재규 ( Jae Gyu Kim ), 김성은 ( Sung Eun Kim ), 양효준 ( Hyo-joon Yang ), 이용찬 ( Yong Chan Lee ), 최일주 ( Il Ju Choi ), 신운건 ( Woon Geon Shin ), 김지현 ( Jie-hyun Kim ), 강승주 ( Seung Joo Kang ), 임현철 ( Hyun Chul Lim ), 박선영 ( Seon-young Park ), 남수연 ( Su Youn Nam ), 정혜경 ( Hye-kyung Jung ) |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
education.field_of_study
medicine.medical_specialty biology business.industry Incidence (epidemiology) Population Evidence-based medicine Guideline Helicobacter pylori biology.organism_classification law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law 030220 oncology & carcinogenesis Internal medicine Clarithromycin medicine 030211 gastroenterology & hepatology Helicobacter education business medicine.drug |
| Zdroj: | The Korean Journal of Medicine. 96:160-189 |
| ISSN: | 2289-0769 1738-9364 |
| DOI: | 10.3904/kjm.2021.96.3.160 |
| Popis: | Helicobacter pylori (H. pylori) infection is one of the most common infectious diseases worldwide. Although its incidence is gradually decreasing, about half of the world''s population still get infected. H. pylori infection is responsible for substantial gastrointestinal morbidity worldwide. It is the most common cause of gastric and duodenal ulcers as well as gastric cancer. Since the revision of the H. pylori Clinical Practice Guidelines in 2013, the eradication rate of H. pylori has gradually decreased with the use of classical triple therapy, wherein amoxicillin, clarithromycin, and proton pump inhibitors are administered, for 7 days. According to a nationwide randomized controlled study conducted by the Korean College of Helicobacter and Upper Gastrointestinal Research released in 2018, the intention-to-treat eradication rate was only 63.9%, which was due to increased antimicrobial resistance induced by the use of antibiotics, especially clarithromycin. The update of clinical practice guideline for treatment of H. pylori was developed based on evidence-based medicine by conducting a meta-analysis. The draft recommendations were finalized after expert consensus on three recommendations regarding the indication for treatment and eight recommendations on the treatment itself. These guidelines are designed to provide patients, nurses, medical school students, policymakers, and clinicians with clinical evidence to guide primary care and treatment of H. pylori infection. These may differ from current medical insurance standards and will be revised further, if necessary, based on research-based evidence. (Korean J Med 2021;96:160-189) |
| Databáze: | OpenAIRE |
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