| Autor: | Gayatri Patel, Marc J. Orbach, Ralph A. Dean, Anna Floyd, Vishal Pampanwar, Mark L. Farman, Shelly J. Nolin, Douglas E Brown, Natalia Galadima, Sara L. Tucker, Donald Windham, Cari Soderlund, Nicole M. Donofrio, Ravi Rajagopalon, Thomas K. Mitchell, Stephen E. Diener, Yong-Hwan Lee |
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| Rok vydání: | 2005 |
| Předmět: |
0106 biological sciences
Genetics 0303 health sciences Magnaporthe biology Sequence analysis Applied Mathematics Computational biology biology.organism_classification 01 natural sciences Biochemistry Genome Computer Science Applications 03 medical and health sciences Structural Biology Component (UML) DNA Mutational Analysis Magnaporthe grisea Genomic library DNA microarray Molecular Biology 030304 developmental biology 010606 plant biology & botany |
| Zdroj: | BMC Bioinformatics. 6:94 |
| ISSN: | 1471-2105 |
| DOI: | 10.1186/1471-2105-6-94 |
| Popis: | Background Recent advances in sequencing techniques leading to cost reduction have resulted in the generation of a growing number of sequenced eukaryotic genomes. Computational tools greatly assist in defining open reading frames and assigning tentative annotations. However, gene functions cannot be asserted without biological support through, among other things, mutational analysis. In taking a genome-wide approach to functionally annotate an entire organism, in this application the ~11,000 predicted genes in the rice blast fungus (Magnaporthe grisea), an effective platform for tracking and storing both the biological materials created and the data produced across several participating institutions was required. |
| Databáze: | OpenAIRE |
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