PIXE STUDIES ON POTASSIUM AND CALCIUM IN MOUSE BLOOD PLASMA AFTER TRANSPLANTATION OF EL-4 TUMOR CELLS
| Autor: | Shinji Matsumoto, Kunio Oohashi, Mutsumi Kachi, Bunshiro Goto, Akemi Nakamura, Kiyofusa Hoshikawa, Hisamasa Joshima, Itsuro Tamanoi |
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| Rok vydání: | 1995 |
| Předmět: | |
| Zdroj: | International Journal of PIXE. :255-264 |
| ISSN: | 1793-6616 0129-0835 |
| Popis: | The quantitative changes in the elements, amounts of Cl, K, Ca, in blood plasma were measured by PIXE method. The samples were obtained at appropriate intervals after transplantation of EL-4 tumor cells in three strains of mice, C57BL/6J (H-2b), C57BL/10J (abbreviation: B10; H-2b) and A/J (H-2a). Transplanted EL-4 tumor cells proliferated in both strains of C57BL/6J and B10. In A/J mice, transplanted EL-4 cells proliferated about 10 days and then were rejected completely by the immunological reaction according to the difference of major histocompatibility antigens. The amounts of Cl in plasma remained at similar level in the time course in any strains, but K fluctuated in C57BL/6J and B10, and less in A/J. On the other hand, Ca showed always higher values in C57BL/6J than other two strains of mice. In B10 mice, Ca increased just before death, but in A/J it decreased at the time of healing by rejection. These changes of Ca in the three strains of mice were related quantitatively 10 the hematocrit values of these strains of mice after transplantation of EL-4 cells. |
| Databáze: | OpenAIRE |
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