Prescription quality of prolonged antibiotherapy in pediatrics. Impact of ASP program interventions

Autor: Susana Melendo, Pere Soler-Palacín, Meritxell Barnés-Mayolas, Aurora Fernández-Polo, Ivette Castellnou Asens, Natalia Mendoza-Palomar
Rok vydání: 2021
Předmět:
Zdroj: Enfermedades infecciosas y microbiologia clinica (English ed.). 39:134-138
ISSN: 2529-993X
Popis: Introduction The duration adequacy of antibiotic regimens is one of the key points of Antimicrobial Stewardship Programs (ASP) given the relationship between the risk of resistance and days of exposure to antimicrobials. Methods Monitoring activities of intravenous antibiotics longer than 7 days at Hospital Infantil Vall d’Hebron, Barcelona, by reviewing data over a 34-weeks period from weekly cross-sectional analysis, followed by recommendations to prescribers to adapt their use. Results A total of 81 patients with 146 prolonged intravenous antibiotic treatments (78.8% of prescriptions were adequate) were reviewed. A total of 190 revisions were performed. 31 interventions on inappropriate prescriptions were carried out (61.3% of adherence to recommendation). Nineteen treatments were optimized (14 suspended, 5 de-escalated) reducing their duration by 8.75%. Conclusions Active intervention of ASP group is an effective tool to improve antibiotic optimization, reducing unnecessarily prolonged treatments, mainly on these areas with a greater range of improvement.
Databáze: OpenAIRE