| Autor: |
Shrikant M. Ghodse, Vikas N. Telvekar, Navnath T. Hatvate, Krishna N. Mundlod |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Letters in Organic Chemistry. 17:613-617 |
| ISSN: |
1570-1786 |
| DOI: |
10.2174/1570178617666191126095808 |
| Popis: |
Metal-free synthesis of pyrimidinone (alky/aryl) via Biginelli reaction in the presence of aqueous sodium dichloroiodate (NaICl2) was studied under reflux conditions. Herein, we first time report the synthesis of the aliphatic Biginelli product by using aliphatic aldehyde, cyclopentane, and urea. Several aromatic and heteroaromatic aldehydes were studied for the confirmation of the wide applicability of aq. NaICl2 for the synthesis of corresponding Biginelli products. The obtained desired products provide good to excellent yield. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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