Intrakardiale Impedanzmessung zur Bestimmung der Sympathikusaktivität bei frequenzadaptiver Elektrostimulation - Teil 2: Klinische Ergebnisse - Intracardiac Impedance to Determine Sympathetic Activity in Rate-Responsive Pacing - Part 2: Clinical Results
| Autor: | A. Urbaszek, W. Niederlag, Max Schaldach, E. Ebner, H. Volkmann, E. Wunderlich, O. T. Greco, W. Rentsch, D. Weber, J. Witte, Helmut Hutten, A. M. Pichlmaier, Domingo Marcolino Braile, G. H. von Knorre |
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| Rok vydání: | 1992 |
| Předmět: |
Chronotropic
medicine.medical_specialty Sympathetic nervous system Cardiac output Baroreceptor medicine.diagnostic_test business.industry Biomedical Engineering Intracardiac injection Impedance cardiography medicine.anatomical_structure Blood pressure Internal medicine Heart rate medicine Cardiology business |
| Zdroj: | Biomedizinische Technik/Biomedical Engineering. 37:188-193 |
| ISSN: | 1862-278X 0013-5585 |
| DOI: | 10.1515/bmte.1992.37.9.188 |
| Popis: | The results of a multicenter clinical study involving patients receiving the first ANS controlled rate adaptive pacemaker are presented. In the patients with primary or secondary chronotropic insufficiency, it is possible to reestablish the closed loop control system that includes the baroreceptors, the medulla oblongata, the cardiac output and the mean arterial blood pressure. This system serves to keep the blood pressure constant in the face of changing demands on the circulation. Utilizing intracardiac impedance measurements, the myocardial contractility can be determined, which contains information about the current sympathetic tone, and thus represents an excellent physiological input for a rate adaptive mechanism. The results presented are taken from a study population of over 200 patients. The objective evaluation of this new approach was performed echocardiographically, by ergometry and 24-hour Holter monitoring. |
| Databáze: | OpenAIRE |
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