Early Cardiac Changes Due to Doxorubicin Based Chemotherapy and Radiotherapy in Early and Locally Advanced Carcinoma Breast Patients: An Observational Study

Autor:	Sudhakar Kotlapati, N. V. Vinin, Ajithananathakrishna Pillai, K. S. Reddy, Dhanapathi Halanaik, Shyama Prem S
Rok vydání:	2015
Předmět:	medicine.medical_specialty Cardiotoxicity Chemotherapy Anthracycline business.industry medicine.medical_treatment Urology Radionuclide ventriculography medicine.disease Surgery Radiation therapy Breast cancer medicine Doxorubicin business Prospective cohort study medicine.drug
Zdroj:	Journal of Nuclear Medicine & Radiation Therapy.
ISSN:	2155-9619
DOI:	10.4172/2155-9619.s7-004
Popis:	Objective: To evaluate prospectively the early cardiac changes from doxorubicin based chemotherapy and radiotherapy in breast cancer patients. Methods and Materials: 56 patients with early or locally advanced breast cancer were included in the study. ECG, ECHO and Equilibrium Radionuclide Ventriculography (ERV) was done at baseline, after chemotherapy, after radiotherapy and at 6 months of follow up. Results: In Group 1 patients who completed six cycles of chemotherapy before starting radiation, the mean LVEF decreased after chemotherapy and after RT(from 66.79 ± 3.73 to 63.45 ± 3.54 and 61.64 ± 4.26, p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e88bd9f28b3c76b5d2a6e2d60fa77dae https://doi.org/10.4172/2155-9619.s7-004 Zobrazit plný text záznamu