Partial Synthesis of [1β,2α,17,17-D4] Gibberellin A1

Autor: Andrea Porzel, Gernot Schneider, Petra Fuchs
Rok vydání: 1997
Předmět:
Zdroj: Journal für Praktische Chemie/Chemiker-Zeitung. 339:448-452
ISSN: 1521-3897
0941-1216
Popis: An efficient route for an alternative synthesis of gibberllin A1 from gibberellin A3 is described. Based on iodolactonisation the method provides access to gibberellin A1 labeled by deuterium with both high incorporation of the isotope and high stereoselectity at the positions 1β and 2α. The additional deuterium labeling at C-17 was introduced via the corresponding 16-norketone resulting in [1β,2α,17,17-D4] gibberellin A1.
Databáze: OpenAIRE
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