Sézary-Syndrom: Variabilität der immunzytologischen und zytochemischen diagnostischen Parameter

Autor:	Konrads A, J. Zach, Meurer Ka, W. Steinbrich, B. Mödder, Schaefer He, G. R. F. Krueger, U. Laaser, Hummerich W, R. Lang
Rok vydání:	2008
Předmět:	Pathology medicine.medical_specialty medicine.diagnostic_test business.industry Autopsy General Medicine Peripheral blood Generalized erythrodermia Complete regression Biopsy medicine sense organs skin and connective tissue diseases Skin pathology business Sezary Cell
Zdroj:	DMW - Deutsche Medizinische Wochenschrift. 105:378-383
ISSN:	1439-4413 0012-0472
DOI:	10.1055/s-2008-1070670
Popis:	Morphological demonstration of the typical Sezary cell in peripheral blood confirmed the diagnosis of Sezary syndrome in a 64-year-old patient with generalized erythrodermia and typical histopathological skin changes. Enzymes and immunocytological membrane characteristics of Sezary cells changed in the course of the disease after cytostatic therapy. Polychemotherapy clinically led to transitory complete regression of skin changes. Reviewing the few published investigations it is found that the morphologically sufficiently defined Sezary cells are apparently not uniform cytochemically and immunocytologically in different patients.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e87ee419ee092eaf5311980b7531479a https://doi.org/10.1055/s-2008-1070670 Zobrazit plný text záznamu