A Multicentre Based Observation of a Screening tool to Differentiate Microcytosis and Hypochromia
| Autor: | Hafizur Rahman, Tashmim Farhana Dipta, Amin Lutful Kabir, Nafisa Fatema, Ahmed Zahid Hossain, Shamima Ferdousi, Gazi Sharmin Sultana |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Pediatrics education.field_of_study business.industry Microcytosis Population General Medicine Iron deficiency medicine.disease Gastroenterology Hypochromic microcytic anemia Iron-deficiency anemia hemic and lymphatic diseases Internal medicine Obligate carrier Hypochromia Medicine business education Mass screening |
| Zdroj: | Anwer Khan Modern Medical College Journal. 7:5-10 |
| ISSN: | 2304-5701 2221-836X |
| DOI: | 10.3329/akmmcj.v7i1.31600 |
| Popis: | Back ground: Iron deficiency anemia (IDA) and beta-thalassaemia trait (B-TT) are the most common causes of hypochromic microcytic anemia. Many indices have been defined to quickly discriminate these similar entities via parameters obtained from automated blood count analyzers.Methodology: The purpose of the study was to evaluate the predictive value of these indices in differential diagnosis of IDA and B-TT in adult cases. In this study we use auto-analyzer based formula of percentages of microcytic and hypochromic red cells (M/H ratio=% of Microcytosis/% of Hypochromia) as a screening tool for thalassaemia trait in Bangladeshi population.Results: A total of 150 subjects w ere included in this study with 50 known obligate carrier of beta-thalassaemia trait and 100 patients with hypochromia and microcytosis. Confirmatory tests for IDA were performed if serum ferritin level was 3.5% , on agarose gel Haemoglobin electrophoresis at an alkaline pH (8.6) where, in addition, MCV 3.5%, while the non- BTT group were those with HbA2 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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