Stereochemistry of Substrate Binding and Hydrolysis in the Trypsin Family of Enzymes
Autor: | D. M. Blow |
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Rok vydání: | 1974 |
Předmět: | |
Zdroj: | Bayer-Symposium ISBN: 9783642879685 |
Popis: | This introductory review aims to describe the three-dimensional molecular structure found at the active site of crystalline trypsin and its homologues; to show how small substrate analogues and inhibitors have been found to interact with the active site of crystals; to relate these structural observations to our knowledge of the specificity of these enzymes; and to indicate how they can be reconciled with our ideas of the catalytic mechanism. |
Databáze: | OpenAIRE |
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