Stereochemistry of Substrate Binding and Hydrolysis in the Trypsin Family of Enzymes

Autor: D. M. Blow
Rok vydání: 1974
Předmět:
Zdroj: Bayer-Symposium ISBN: 9783642879685
Popis: This introductory review aims to describe the three-dimensional molecular structure found at the active site of crystalline trypsin and its homologues; to show how small substrate analogues and inhibitors have been found to interact with the active site of crystals; to relate these structural observations to our knowledge of the specificity of these enzymes; and to indicate how they can be reconciled with our ideas of the catalytic mechanism.
Databáze: OpenAIRE