Assessment of Serum Anti-Müllerian Hormone (AMH) as an Independent Marker for Oligozoospermia and Non-Obstructive Azoospermia in Infertile Nigerian Men
| Autor: | Olaniru B. Olumide, Adoga I. Godwin, Johnson O. Titilayo, Isichei O. Christian, Nkereuwem S. Etukudoh, Obeta M. Uchejeso, Selowo T. Temitope, Sulagna Dutta, Pallav Sengupta |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Biomedical and Pharmacology Journal. 16:35-42 |
| ISSN: | 2456-2610 0974-6242 |
| DOI: | 10.13005/bpj/2585 |
| Popis: | Background: Anti-Müllerian hormone (AMH) is a Sertoli cell-derived glycoprotein that mediates regression of Müllerian duct in male embryos. The present study aims to evaluate the diagnostic efficacy of serum AMH in the detection of oligozoospermia and non-obstructive azoospermia (NOA) in a homogenous population of Nigerian men. Methods: This case-controlled prospective study was conducted on eighty male subjects (aged 18-45 years), at the Jos University Teaching Hospital, Nigeria. Subjects were classified as control (n=30), oligozoospermic (n=27) and non-obstructive azoospermia (NOA; n=23) (World Health Organization, 2010). Serum concentrations of various hormones were measured. Statistical analyses were performed using MedCalc. (v.19.5.1, Ostend, Belgium). Results: Serum AMH levels did not differ significantly among the study groups (P>0.05). Serum levels of testosterone were significantly lower, while serum FSH levels were significantly higher in the infertile groups than the control (P |
| Databáze: | OpenAIRE |
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