Treatment of Infraorbital Dark Circles Using a Low-Fluence Q-Switched 1,064-nm Laser

Autor: Ting Xiao, Hong-Duo Chen, Zhen-Hai Yang, Yuan-Hong Li, Tian-Hua Xu, Wei Liu, Long Geng, John Z S Chen, Shu Guo, Xing-Hua Gao, Yan Wu, Chundi He
Rok vydání: 2011
Předmět:
Zdroj: Dermatologic Surgery. 37:797-803
ISSN: 1076-0512
DOI: 10.1111/j.1524-4725.2011.01956..x
Popis: OBJECTIVE To evaluate the efficacy and safety of the low-fluence 1,064-nm Q-switched neodymium-doped yttrium aluminium garnet (QSNY) laser in treating infraorbital dark circles. PARTICIPANTS AND METHODS Thirty women with infraorbital dark circles (predominant color dark brown) participated in this open-label study. Participants underwent eight sessions of low-fluence QSNY laser treatment at 4.2 J/cm2 at 3- to 4-day intervals. A spot size of 3.5 mm was used, with a pulse duration of 8 ns. The melanin deposition in the lesional skin was observed in vivo using reflectance confocal microscopy (RCM). Morphologic changes were evaluated using a global evaluation, an overall self-assessment, a narrow-band reflectance spectrophotometer, and a skin hydration measurement instrument. RESULTS Twenty-six of 30 patients showed global improvement that they rated as excellent or good. Twenty-eight rated their overall satisfaction as excellent or good. The melanin index indicated a substantial decrease, from 225.84 at baseline to 182.65 (p
Databáze: OpenAIRE