Mucormycosis – Can the diagnosis be challenging at times??
| Autor: | C Geetha Kiran, Vandana Raghunath, R Manasa Deepthi, K Hanna Rose Priyanka |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty business.industry medicine.medical_treatment 030106 microbiology Mucormycosis H&E stain Immunosuppression 030206 dentistry medicine.disease Oral cavity Grocott's methenamine silver stain Dermatology 03 medical and health sciences 0302 clinical medicine Paranasal sinuses medicine.anatomical_structure Medicine business Sinus (anatomy) |
| Zdroj: | SRM Journal of Research in Dental Sciences. 9:191 |
| ISSN: | 0976-433X |
| DOI: | 10.4103/srmjrds.srmjrds_53_18 |
| Popis: | Mucormycosis is an aggressive and often rapidly progressing fatal form of fungal infection mainly affecting the immunocompromised patients and characterized by destruction and necrosis. The paranasal sinuses get affected commonly in the rhinocerebral type with or without oral cavity involvement. At times, even in the setting of immunosuppression, it presents as a subtle clinical infection posing both as a diagnostic and therapeutic challenge to the clinicians. Further, in such immunocompromised cases, early diagnosis and prompt treatment become utmost demanding to prevent the ensuing morbidity and mortality. We present one such indolent case which presented as a sinus infection in a 50-year-old diabetic woman. Further, the granulomatous presentation on hematoxylin and eosin-stained sections led to an erroneous initial diagnosis, which later upon Grocott's methenamine silver staining was diagnosed as mucormycosis-rhinocerebral type. Thus, both clinical and histopathological presentations were defying. |
| Databáze: | OpenAIRE |
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