| Autor: |
Aaron D Cooper, Walter R Koehler, John J Czarnecki |
| Rok vydání: |
1979 |
| Předmět: |
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| Zdroj: |
Journal of AOAC INTERNATIONAL. 62:15-18 |
| ISSN: |
0004-5756 |
| DOI: |
10.1093/jaoac/62.1.15 |
| Popis: |
A gas-liquid chromatographic (GLC) headspace technique is described for determining sodium bisulfite in a dermatological cream. The sample is dispersed in an aqueous medium and acidified to convert sulfite to volatile sulfur dioxide which partitions into the headspace. An aliquot of the headspace vapor is analyzed by GLC using the sulfur-selective flame photometric detector. Advantages of the method include the facility of sample preparation, the specificity and sensitivity resulting from the combined use of the headspace technique and the flame photometric detector, and the applicability of the method to various types of sample matrices. Recoveries ranged from 95 to 102% for spiked samples containing 200—2000 ppm sodium bisulfite. For the sample size and experimental conditions used in this application, the detection limit is 0.02 mg sodium bisulfite. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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