Unusual Synthesis and Cytotoxicity of N-[2-(Benzothiazol-2-Sulfonyl)-1-Ethoxyethoxy]- 5-(Benzothiazol-2-Ylsulfanyl)Pentanamidine

Autor:	A. Gulbe, E. Jaščenko, E. Ābele, I. Šestakova, J. Višņevska
Rok vydání:	2012
Předmět:	Sulfonyl chemistry.chemical_classification chemistry.chemical_compound Benzothiazole Chemistry Cytotoxicity Medicinal chemistry
Zdroj:	Latvian Journal of Chemistry. 51:149-153
ISSN:	0868-8249
DOI:	10.2478/v10161-012-0003-1
Popis:	Unusual Synthesis and Cytotoxicity of N-[2-(Benzothiazol-2-Sulfonyl)-1-Ethoxyethoxy]- 5-(Benzothiazol-2-Ylsulfanyl)PentanamidineAddition of N-hydroxy-5-(benzothiazolylthio)pentanamidine toE-2-(2-chlorovinylsulfonyl)benzothiazole in the presence of NaH was studied. The main product of reaction - N-[2-(benzothiazol-2-sulfonyl)-1-ethoxyethoxy]-5-(benzothiazol-2-ylsulfanyl)pentanamidine exhibits high cytotoxicity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e8214711e7c96a42244755791a1b0ae3 https://doi.org/10.2478/v10161-012-0003-1 Zobrazit plný text záznamu