Chemoselective bicyclobutane-based mass spectrometric detection of biological thiols uncovers human and bacterial metabolites

Autor: Amanpreet Kaur, Weifeng Lin, Vladyslav Dovhalyuk, Léna Driutti, Maria Letizia Di Martino, Miroslav Vujasinovic, J.-Matthias Löhr, Mikael E. Sellin, Daniel Globisch
Rok vydání: 2023
Předmět:
Zdroj: Chemical Science. 14:5291-5301
ISSN: 2041-6539
2041-6520
DOI: 10.1039/d3sc00224a
Popis: Thiol-containing metabolites in all organisms are involved in the regulation of diverse biological processes. We have developed a new method comprising bicyclobutane for chemoselective capturing and mass spectrometric analysis of this compound class.
Databáze: OpenAIRE