Rôle des ponts disulfure dans le repliement en épingle à cheveux de l’androctonine. Relations structure–activité

Autor:	Charles Hetru, Henri Labbé, Céline Landon, Nicolas Mandard, Pedro da Silva, Françoise Vovelle
Rok vydání:	2001
Předmět:	0303 health sciences animal structures biology Chemistry Stereochemistry Androctonus australis 030303 biophysics Disulfide bond General Chemistry biology.organism_classification Antibacterial peptide 03 medical and health sciences Hemolymph 030304 developmental biology
Zdroj:	Comptes Rendus de l'Académie des Sciences - Series IIC - Chemistry. 4:735-738
ISSN:	1387-1609
DOI:	10.1016/s1387-1609(01)01297-x
Popis:	Androctonin is a 25-residue antibacterial peptide extracted from the hemolymph of the scorpion Androctonus australis. In order to understand the structural requirements for hairpin fold and for interactions with the bacterial membrane, we have analysed the chemical shifts and the nOes of three synthetic androctonin mutants for which the disulfide bridges were selectively removed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e80389b552875ae404e8ff1658bb2ec0 https://doi.org/10.1016/s1387-1609(01)01297-x Zobrazit plný text záznamu