| Autor: |
Allen, Coburn H, Goldman, Ran D, Bhatt, Seema, Simon, Harold K, Gorelick, Marc H, Spandorfer, Philip R, Spiro, David M, Mace, Sharon E, Johnson, David W, Higginbotham, Eric A, Du, Hongyan, Smyth, Brendan J, Schermer, Carol R, Goldstein, Stuart L |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| DOI: |
10.14288/1.0366843 |
| Popis: |
Background: Compare the efficacy and safety of Plasma-Lyte A (PLA) versus 0.9 % sodium chloride (NaCl) intravenous (IV) fluid replacement in children with moderate to severe dehydration secondary to acute gastroenteritis (AGE). Methods: Prospective, randomized, double-blind study conducted at eight pediatric emergency departments (EDs) in the US and Canada (NCT#01234883). The primary outcome measure was serum bicarbonate level at 4 h. Secondary outcomes included safety and tolerability. The hypothesis was that PLA would be superior to 0.9 % NaCl in improvement of 4-h bicarbonate. Patients (n = 100) aged ≥6 months to |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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