Additional file 4: Figure S4. of Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration

Autor: Ohki, Yu, Wenninger-Weinzierl, Andrea, Hruscha, Alexander, Asakawa, Kazuhide, Kawakami, Koichi, Haass, Christian, Edbauer, Dieter, Schmid, Bettina
Rok vydání: 2017
Předmět:
DOI: 10.6084/m9.figshare.c.3666376_d7.v1
Popis: Muscle patterning is not affected. (A) Quantification of GFP inclusions in GA80-GFPa and GA80-GFPb larvae subdivided into mild and strong edema phenotypes at 4 dpf. (n = 4 per subgroup, mean ± SD). Amount of inclusions from GA80-GFP line a and b with mild and strong phenotypes were not significantly different (paired t-test). Inclusions were exclusively detected in the musculature in both lines. (B) The overall structure of the muscle was analyzed by α-actinin staining at 2 dpf in a GFP negative GA80-GFP embryo and (B) GFP positive sibling. Scale bar 20 μm. (PDF 3472 kb)
Databáze: OpenAIRE