Synthesis and Cytotoxic Activity of Selenophenfurin, a New Inhibitor of IMP Dehydrogenase

Autor: G. Perra, T. Sint, G. Abu Sheikha, S. Poma, Mario Grifantini, Barry M. Goldstein, Loredana Cappellacci, Palmarisa Franchetti, P. La Colla, H. N. Jayaram, Bryan P. Schneider, V. V. Gurudutt
Rok vydání: 1997
Předmět:
Zdroj: Nucleosides and Nucleotides. 16:1045-1048
ISSN: 0732-8311
Popis: The synthesis of 5-β-D-ribofuranosylselenophene-3-carboxamide (selenophenfurin) is reported. Selenophenfurin was found active as cytotoxic agent and as inosine monophosphate dehydrogenase inhibitor.
Databáze: OpenAIRE