Aerosol Deposition in the Human Lung at Variable Tidal Volumes: Calculation of Fractional Deposition

Autor: S J Rothenberg, D L Swift
Rok vydání: 1984
Předmět:
Zdroj: Aerosol Science and Technology. 3:215-226
ISSN: 1521-7388
0278-6826
DOI: 10.1080/02786828408959009
Popis: The calculation of fractional aerosol deposition in the human lung and methods for correction of breath-by-breath deposition data for inequalities in tidal volume are discussed. Three different methods are considered. Steady state and wash-in curves are used to evaluate methods presented herein. Plots of breath-by-breath deposition data against the ratio of volume exhaled to volume inhaled give linear plots of similar slope for a range of steady state breathing patterns for both 0.5- and 1.2-μm particles. Semiempirical algebraic correction factors are found to be suitable for analysis of wash-in curves.
Databáze: OpenAIRE