Synthesis of 3,4-bischloromethyl-1,2,5-thiadiazole: an unexpected chloromethylation; contrasting selectivity in dihalogenations by N-chlorosuccinimide and N-bromosuccinimide

Autor:	Alan C. Richards, Ronald F. Cookson
Rok vydání:	1974
Předmět:	N-Chlorosuccinimide chemistry.chemical_compound Electrophilic substitution chemistry Molecular Medicine Organic chemistry N-Bromosuccinimide Selectivity
Zdroj:	Journal of the Chemical Society, Chemical Communications. :585
ISSN:	0022-4936
DOI:	10.1039/c39740000585
Popis:	1,2,5-Thiadiazole, previously thought to be resistant to electrophilic substitution, has been shown to undergo chloromethylation; N-chlorosuccinimide is more selective than N-bromosuccinimide in the dihalogenation of 3,4-dimethyl-1,2,5-thiadiazole.
Databáze:	OpenAIRE
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