A practical, two-stage preparation of benzyl (3R)-3-amino-2-oxo-1-pyrrolidinecarboxylate (2S,3S)-2,3-bis[(4-methylbenzoyl)oxy]butanediote (2:1)

Autor: Peter W. Scott, Åsa Sjolin, Ron M. Lawrence, Jason W. B. Cooke, Roger Barrett, Darren Caine, Kevin S. Cardwell
Rok vydání: 2003
Předmět:
Zdroj: Tetrahedron: Asymmetry. 14:3627-3631
ISSN: 0957-4166
DOI: 10.1016/s0957-4166(03)00546-9
Popis: A convenient, efficient and cost-effective two-stage synthesis of benzyl (3R)-3-amino-2-oxo-1-pyrrolidinecarboxylate (2S,3S)-2,3-bis[(4-methylbenzoyl)oxy]butanediote (2:1) via a crystallisation-induced dynamic resolution process is reported.
Databáze: OpenAIRE