Elexacaftor/tezacaftor/ivacaftor Treatment Reduces Airway Inflammation in Cystic Fibrosis
Autor: | Richard C. De Vuyst, Erin Bennard, Charissa Kam, Cameron McKinzie, Charles Esther |
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Rok vydání: | 2022 |
DOI: | 10.22541/au.167170864.42960149/v1 |
Popis: | ETI treatment reduces inflammatory markers and positive bacterial cultures on BAL in PwCF. These findings suggest that ETI has a greater impact on chronic infection and inflammation than ivacaftor alone. However, airway inflammation persists in a fraction of treated individuals, indicating an ongoing need to optimize other treatments in a subset of patients. |
Databáze: | OpenAIRE |
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