Elexacaftor/tezacaftor/ivacaftor Treatment Reduces Airway Inflammation in Cystic Fibrosis

Autor: Richard C. De Vuyst, Erin Bennard, Charissa Kam, Cameron McKinzie, Charles Esther
Rok vydání: 2022
DOI: 10.22541/au.167170864.42960149/v1
Popis: ETI treatment reduces inflammatory markers and positive bacterial cultures on BAL in PwCF. These findings suggest that ETI has a greater impact on chronic infection and inflammation than ivacaftor alone. However, airway inflammation persists in a fraction of treated individuals, indicating an ongoing need to optimize other treatments in a subset of patients.
Databáze: OpenAIRE