Mechanical performance and implications on bone healing of different screw configurations for plate fixation of diaphyseal tibia fractures: a computational study
| Autor: | Francesco Travascio, Leonard T. Buller, Edward Milne, Loren L. Latta |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
musculoskeletal diseases
Orthodontics 030222 orthopedics business.industry 0206 medical engineering Fracture site Stiffness 02 engineering and technology Bone healing equipment and supplies musculoskeletal system 020601 biomedical engineering Finite element method 03 medical and health sciences Fixation (surgical) surgical procedures operative 0302 clinical medicine medicine Orthopedics and Sports Medicine Surgery Tibia medicine.symptom business Bone regeneration Plate fixation |
| Zdroj: | European Journal of Orthopaedic Surgery & Traumatology. 31:121-130 |
| ISSN: | 1432-1068 1633-8065 |
| DOI: | 10.1007/s00590-020-02749-5 |
| Popis: | Diaphyseal tibia fractures may require plate fixation for proper healing to occur. Currently, there is no consensus on the number of screws required for proper fixation or the optimal placement of the screws within the plate. Mechanical stability of the construct is a leading criterion for choosing plate and screws configuration. However, number and location of screws have implications on the mechanical environment at the fracture site and, consequently, on bone healing response: The interfragmentary motion attained with a specific plate and screw construct may elicit mechano-transduction signals influencing cell-type differentiation, which in turn affects how well the fracture heals. This study investigated how different screw configurations affect mechanical performance of a tibia plate fixation construct. Three configurations of an eight-hole plate were considered with the fracture in the center of the plate: eight screws-screws at first, fourth, fifth and eighth hole and screws at first, third, sixth and eighth hole. Constructs' stiffness was compared through biomechanical tests on bone surrogates. A finite element model of tibia diaphyseal fracture was used to conduct a stress analysis on the implanted hardware. Finally, the potential for bone regeneration of each screw configuration was assessed via the computational model through the evaluation of the magnitude of mechano-transduction signals at the bone callus. The results of this study indicate that having screws at fourth and fifth holes represents a preferable configuration since it provides mechanical properties similar to those attained by the stiffest construct (eight screws), and elicits an ideal bone regenerative response. |
| Databáze: | OpenAIRE |
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