DETERMINATION OF PSEUDOEPHEDRINE HYDROCHLORIDE AND TRIPROLIDINE HYDROCHLORIDE SIMULTANEOUSLY BY USING AREA UNDER CURVE SPECTROPHOTOMETRY ULTRAVIOLET

Autor:	R. E. Tarigan, D. M. Sianturi, null S. Nadya
Rok vydání:	2023
Předmět:	General Energy General Chemical Engineering General Chemistry General Pharmacology Toxicology and Pharmaceutics Biochemistry
Zdroj:	RASAYAN Journal of Chemistry. 16:223-226
ISSN:	0976-0083 0974-1496
DOI:	10.31788/rjc.2023.1618072
Popis:	Anti-influenza drugs on the market contain a combination of more than one active substance in one preparation. An example is pseudoephedrine hydrochloride and triprolidine hydrochloride in tablet form. The goal of this research is to determine pseudoephedrine hydrochloride and triprolidine hydrochloride simultaneously by using the area under curve spectrophotometry. The area under the curve in the wavelength range of 306.6-316.6 nm and 253.6-263.6 nm were selected to determine pseudoephedrine hydrochloride and triprolidine hydrochloride, respectively. The method was linear at a concentration range of 180-500 μg/mL (correlation coefficient 0,9994) and 6-18 μg/mL (correlation coefficient 0,9996) for the pseudoephedrine hydrochloride and triprolidine hydrochloride, respectively. The mean % recoveries for pseudoephedrine hydrochloride and triprolidine hydrochloride were 100.01% and 100.07%, respectively. This method was successfully used to determine pseudoephedrine hydrochloride and triprolidine hydrochloride simultaneously.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e77ea963975580cf0e420741f04ba1c6 https://doi.org/10.31788/rjc.2023.1618072 Zobrazit plný text záznamu Plný text ve formátu PDF