Full Range of Vasodilation Tested by Transcranial Doppler in the Differential Diagnosis of Vascular and Alzheimer Types of Dementia

Autor: Eduardo Varela de Seijas, Marisa Barquero, Jose Antonio Egido, Alberto Marcos, Cristina Fernández
Rok vydání: 1997
Předmět:
Zdroj: Cerebrovascular Diseases. 7:14-18
ISSN: 1421-9786
1015-9770
DOI: 10.1159/000108157
Popis: The aim of this study is to validate whether measuring the cerebral vasomotor response with the breath-holding method can be a useful technique in the differentiation of vascular and Alzheimer types of dementia. We adopted the clinical and neuropsychological diagnosis of dementia according to DSM-IV criteria as the standard diagnosis against which our method was compared. Resting middle cerebral artery velocity, its rate of increase on breath holding and its decrease on hyperventilation (full range of vasodilation, FRV) were measured using a transcranial Doppler (TCD) velocimeter on both sides in a prospective study on 32 age-matched controls, 36 patients diagnosed with Alzheimer type dementia, and 31 vascular dementia (VD) patients. A total of 186 vessels were studied in 99 patients. A high level of significance (p
Databáze: OpenAIRE