Design and synthesis of spirooxindole–pyrrolidines embedded with indole and pyridine heterocycles by multicomponent reaction: anticancer and in silico studies

Autor: Sivakalai Mayakrishnan, Devarajan Kathirvelan, Yuvaraj Arun, Krishnan Saranraj, Chandrasekaran Balachandran, Shin Aoki, Pannerselvam Yuvaraj, Narayanan Uma Maheswarai
Rok vydání: 2022
Předmět:
Zdroj: New Journal of Chemistry. 46:10089-10106
ISSN: 1369-9261
1144-0546
Popis: We report the synthesis of spirooxindole–pyrrolidines tethered with indole and pyridine heterocycles using 1,3-dipolar cycloaddition, and their anticancer activities and molecular docking studies.
Databáze: OpenAIRE