Design and synthesis of spirooxindole–pyrrolidines embedded with indole and pyridine heterocycles by multicomponent reaction: anticancer and in silico studies
Autor: | Sivakalai Mayakrishnan, Devarajan Kathirvelan, Yuvaraj Arun, Krishnan Saranraj, Chandrasekaran Balachandran, Shin Aoki, Pannerselvam Yuvaraj, Narayanan Uma Maheswarai |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | New Journal of Chemistry. 46:10089-10106 |
ISSN: | 1369-9261 1144-0546 |
Popis: | We report the synthesis of spirooxindole–pyrrolidines tethered with indole and pyridine heterocycles using 1,3-dipolar cycloaddition, and their anticancer activities and molecular docking studies. |
Databáze: | OpenAIRE |
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