Safety of central venous catheter placement at diagnosis of acute lymphoblastic leukemia in children
| Autor: | Amy W. Wozniak, C H Pui, Bhaskar N. Rao, Andrew M. Davidoff, G. Gonzalez, Stephen J. Shochat, Scott C. Howard, Jerry L. Shenep |
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| Rok vydání: | 2011 |
| Předmět: |
medicine.medical_specialty
Pediatrics business.industry medicine.medical_treatment Incidence (epidemiology) Retrospective cohort study Hematology equipment and supplies medicine.disease Pediatric cancer Thrombosis Surgery Catheter Oncology Pediatrics Perinatology and Child Health medicine Infection control business Central venous catheter Cohort study |
| Zdroj: | Pediatric Blood & Cancer. 58:498-502 |
| ISSN: | 1545-5009 |
| DOI: | 10.1002/pbc.24010 |
| Popis: | Background Central venous catheters (CVC) facilitate the management of patients with cancer. Optimal timing for placement of a CVC is controversial. We sought to determine whether early placement in children with acute lymphoblastic leukemia (ALL), a group at high risk for infection and thrombosis, was associated with an increased rate of surgical complications. Procedure We evaluated the incidence and risk factors for early surgical complications in children with ALL diagnosed between 2004 and 2009 at a single pediatric cancer center. Results One hundred seventy-two patients were studied. There were 17 episodes of bloodstream infection, for a 30-day incidence of 9.8% (95% CI, 5.9–15%). There were no surgical site infections and no CVC was removed due to infection. Early thrombosis occurred in only one patient, 3 days after CVC placement. Infection was not influenced by catheter type, patient age, body mass index, or fever at the time of placement. The infection rate was not statistically higher when the ANC was |
| Databáze: | OpenAIRE |
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