Inhibition of the growth of malignant mouse lymphoid cells by selenodiglutathione and selenodicysteine

Autor:	W.S. Bont, C.J. Homburg, L.N. Vernie
Rok vydání:	1981
Předmět:	Cancer Research Cell number Dye exclusion Biology Selenodicysteine Molecular biology chemistry.chemical_compound Oncology chemistry Selenodiglutathione Untreated control Immunology Ascites medicine Trypan blue Tumor growth medicine.symptom
Zdroj:	Cancer Letters. 14:303-308
ISSN:	0304-3835
DOI:	10.1016/0304-3835(81)90159-2
Popis:	Intraperitoneal injections of selenodiglutathione (GSSeSG) or selenodicysteine (CySSeSCy) in mice, previously inoculated with tumor cells, inhibited tumor growth and increased the life span of treated as compared with untreated control mice. Determination of cell number at different times after injection of GSSeSG or CySSeSCy indicated that less tumor cells were present in the ascites fluid of these mice than in control mice. The trypan blue dye exclusion method performed 1 day after the injection of GSSeSG showed a high percentage of dead cells (84–99%).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e74ffcf04e09e21d3a79045db9449cf6 https://doi.org/10.1016/0304-3835(81)90159-2 Zobrazit plný text záznamu