CLINICAL AND EPIDEMIOLOGIC OBSERVATIONS ON ENTEROVIRUS INFECTION IN A CIRCUMSCRIBED COMMUNITY DURING AN EPIDEMIC OF ECHO 9 INFECTION
| Autor: | Frederick C. Robbins, Martha L. Lepow, David H. Carver |
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| Rok vydání: | 1960 |
| Předmět: | |
| Zdroj: | Pediatrics. 26:12-26 |
| ISSN: | 1098-4275 0031-4005 |
| Popis: | A clinical, epidemiologic and laboratory study was undertaken in a housing development during an epidemic of illness due to ECHO virus, type 9. The clinical manifestations varied with age. The younger children exhibited an exanthem while older persons frequently had evidence of irritation of the central nervous system. Multiple cases occurred within families, with the incidence of illness highest in the younger age groups. No serious consequences of the illness were seen. Echo 9 virus was recovered with greater frequency from the intestinal contents of young children with illness than from ill adults, although serologic evidence of recent infection in these adults could be demonstrated. The rate of inapparent infection with ECHO 9 virus was low. Virus rarely persisted in the feces beyond 14 days after onset of illness. Group B Coxsackie viruses, type 4 and type 5, were found also to be the cause of many infections within the same population at the same time. Illnesses due to these viruses were similar to those due to ECHO 9 virus, except that no eruption was observed. The rate of inapparent infection was higher than that observed with ECHO 9 virus. Simultaneous infection with ECHO 9 virus and Coxsackie B4 or B5 virus was rare. |
| Databáze: | OpenAIRE |
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