Digital analysis and quantitative assessment of the cervical surface with dysplasia

Autor: Aleshkin Va, A. D. Dushkin, T. G. Grishacheva, S.S. Afanasiev, Yu.V. Nesvizhsky, M. S. Afanasiev, A Yu Mironov, O.Y. Borisova, Alexander Karaulov, A M Zatevalov
Rok vydání: 2021
Předmět:
Zdroj: Russian Clinical Laboratory Diagnostics. 66:417-421
ISSN: 2412-1320
0869-2084
DOI: 10.51620/0869-2084-2021-66-7-417-421
Popis: The investigation aims - a quantitative assessment of cervical surface changes with digital analysis and computer technologies in dysplasia. Colposcopy was made in 90 women from 21 to 52 years (avr. age 33,9±8,13 y.o.) with mild epithelial dysplasia (CIN1), moderate dysplasia (CIN2), severe dysplasia (CIN3). The algorithm detected indicators which provide the cervical dysplasia classification on pre cytological and pre molecular-genetic patients investigations. The outcome of an algorithm was the identification of the cervix surface condition severity by an objective quantification. The cervical dysplasia type (CIN) was classified as IndGV values. The mild dysplasia (CIN1) had IndGV=8,5, moderate dysplasia (CIN2) - IndGV=13, severe dysplasia (CIN3) - IndGV=15,6. The cervical affected surface area (IndInt) equalled 0,17 in CIN1, 0,19 in CIN2, 0,22 in CIN3. A change severity has a direct relation with a grey color value. It demonstrates quantify classification in digital analysis. The algorithm is used in real-time mode and no requires considerable material outlays. This makes it possible to use an algorithm after clinical examination and predict patient management.
Databáze: OpenAIRE