| Popis: |
The aim of the experiments was to investigate the protective effect of resveratrol c o - administration with cholesterol diet on erythrocyte osmotic fragility (EOF) and malondialdehyde (MDA) concentration in rabbits. Thirty rabbits divided into six group of five animals (n = 5) each were used for the experiment: Group 1 = normal control (C), group 2 = cholesterol diet (CD) only, group 3 = resveratrol 200 mg/kg (R200), group 4 = resveratrol 400 mg/kg (R400), group 5 = CD + R200 and group 6 = CD + R400. Eight weeks after the treatment period, blood sample of about 5 ml (3 ml in EDTA bottle for erythrocyte osmotic fragility ( EOF ) test and 2 ml in plane tube for extraction of serum for malondialdehyde concentration ( MDA) were drawn from the heart of each sacrificed Original Research Article |
