Impact of elective percutaneous coronary intervention using second-generation drug-eluting stents on late mortality compared with medical treatment or coronary artery bypass surgery: A systematic review and meta-analysis

Autor: Borger, Michael, Gomes, Walter Jose, Flumignan, Ronald Luiz Gomes, Guizilini, Solange, Rocco, Isadora Salvador, Paez, Rodrigo Pereira, Marin-Cuartas, Mateo
Rok vydání: 2023
Předmět:
DOI: 10.17605/osf.io/5qhyz
Popis: Recent randomized clinical trials have reported an increased late mortality after percutaneous coronary interventions (PCI) with second generation drug-eluted stents (DES) – those eluted with everolimus or zotarolimus – when compared to optimized clinical therapy or coronary artery bypass grafting (CABG). Those increased late mortality has been related to cancer and chronic diseases. This study will be a systematic review and meta-analysis that aims to elucidate whether PCI raises or not late mortality, the cause of mortality and its relationship with the number of stents used, left ventricular function, age, sex, and number of vessels obstructed.
Databáze: OpenAIRE