Visible-Light-Triggered Uncaging of Carbonyl Sulfide for Hydrogen Sulfide (H2S) Release
| Autor: | Mrutyunjay A. Nair, Ajay Sharma, Kavya Gupta, Harinath Chakrapani, Deepak Kumar Saini, Preeti Chauhan |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
chemistry.chemical_classification
biology 010405 organic chemistry Hydrogen sulfide Organic Chemistry chemistry.chemical_element equipment and supplies 010402 general chemistry Photochemistry 01 natural sciences Biochemistry 0104 chemical sciences chemistry.chemical_compound Hydrolysis Enzyme chemistry Carbonic anhydrase biology.protein Physical and Theoretical Chemistry Boron Carbonyl sulfide Visible spectrum |
| Zdroj: | Organic Letters. 19:4822-4825 |
| ISSN: | 1523-7052 1523-7060 |
| DOI: | 10.1021/acs.orglett.7b02259 |
| Popis: | Generation of hydrogen sulfide (H2S) is challenging and few methods are capable of localized delivery of this gas. Here, a boron dipyrromethene-based carbamothioate (BDP-H2S) that is uncaged by visible light of 470 nm to generate carbonyl sulfide (COS), which is rapidly hydrolyzed to H2S in the presence of carbonic anhydrase, a widely prevalent enzyme, is reported. |
| Databáze: | OpenAIRE |
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