Effect of antibodies to glial glycolipid antigens on miniature endplate potentials

Autor:	D. P. Matyushkin, N. P. Taranova, Vinogradova Im, Luchakova Os, M. G. Dobretsov
Rok vydání:	1989
Předmět:	Antiserum medicine.medical_specialty Physiology General Neuroscience Biology Acetylcholinesterase Blockade chemistry.chemical_compound Endocrinology Glycolipid Antigen chemistry Internal medicine Immunology Time course medicine biology.protein Galactocerebroside Antibody
Zdroj:	Neurophysiology. 21:164-169
ISSN:	1573-9007 0090-2977
DOI:	10.1007/bf01056976
Popis:	No more than 4% of the miniature endplate potentials (MEPP) recorded in preparations of frog cutaneous pectoral muscle kept in Ringers solution or treated with nonimmune rabbit serum were atypical, having a normal amplitude but abnormally retarded (almost doubled) time course. The percentage of atypical MEPP more than tripled after processing preparations with galactocerebroside (GalC) antiserum. Armine-induced blockade of synaptic acetylcholinesterase increased the rate of "giant" MEPP occurrence (but not of those with normal amplitude plus protracted time course). Mechanisms possibly underlying the increased percentage of atypical MEPP during GalC action on Schwann cells are discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e708f4e2b25a411c889ed56dd6ca61e5 https://doi.org/10.1007/bf01056976 Zobrazit plný text záznamu Full text from SpringerLink