THE F(ab???)2 FRAGMENT OF AN ANTI-ICAM-1 MONOCLONAL ANTIBODY ATTENUATES LIVER INJURY AFTER ORTHOTOPIC LIVER TRANSPLANTATION1
Autor: | S Tsuji, Hirotaka Nagai, Sunao Kawano, Kouichi Nagano, Takenobu Kamada, Yoshiya Nishimura, Hideyuki Fusamoto, Moritaka Goto, Atsushi Ohmae, Yoshiyuki Takei |
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Rok vydání: | 1996 |
Předmět: | |
Zdroj: | Transplantation. 61:99-104 |
ISSN: | 0041-1337 |
DOI: | 10.1097/00007890-199601150-00020 |
Popis: | Long-term storage of liver grafts results in increased adhesion of leukocytes onto the sinusoidal walls. This eventually leads to posttransplant graft damage through disturbances of hepatic microcirculation. Intracellular adhesion molecule-1 (ICAM-1) is known to be involved in attachment of leukocyt |
Databáze: | OpenAIRE |
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