THE F(ab???)2 FRAGMENT OF AN ANTI-ICAM-1 MONOCLONAL ANTIBODY ATTENUATES LIVER INJURY AFTER ORTHOTOPIC LIVER TRANSPLANTATION1

Autor: S Tsuji, Hirotaka Nagai, Sunao Kawano, Kouichi Nagano, Takenobu Kamada, Yoshiya Nishimura, Hideyuki Fusamoto, Moritaka Goto, Atsushi Ohmae, Yoshiyuki Takei
Rok vydání: 1996
Předmět:
Zdroj: Transplantation. 61:99-104
ISSN: 0041-1337
DOI: 10.1097/00007890-199601150-00020
Popis: Long-term storage of liver grafts results in increased adhesion of leukocytes onto the sinusoidal walls. This eventually leads to posttransplant graft damage through disturbances of hepatic microcirculation. Intracellular adhesion molecule-1 (ICAM-1) is known to be involved in attachment of leukocyt
Databáze: OpenAIRE