Abdominal Malignant Mesothelioma Following Autologous Bone Marrow Transplantation: A Case Report
Autor: | M. De Simone, S. Orecchia, G. Gorzegno, Irene Tardivo, P. Cacciotti, Roberto Miniero, L. Gubetta |
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Rok vydání: | 2003 |
Předmět: |
Melphalan
medicine.medical_specialty business.industry hemic and immune systems Hematology medicine.disease Surgery surgical procedures operative medicine.anatomical_structure Oncology El Niño Peritoneum hemic and lymphatic diseases Pediatrics Perinatology and Child Health medicine Abdomen Mesothelioma Bone marrow Stem cell Complication business neoplasms medicine.drug |
Zdroj: | Pediatric Hematology and Oncology. 20:583-588 |
ISSN: | 1521-0669 0888-0018 |
DOI: | 10.1080/08880010390242915 |
Popis: | Secondary malignancies are a well-known late complication occurring in patients who undergo bone marrow transplant (BMT) during childhood. A boy with acute lymphoblastic leukemia experienced a BM relapse at the age of 14 years and underwent an autologous BMT conditioned with TBI and melphalan. Sixteen years later a malignant mesothelioma of the peritoneum was diagnosed. A surgical approach according to the Sugarbaker technique and hyperthermic peritoneal perfusion with CDDP and Adriamycin were performed. The patient is alive and well after a follow-up of 20 months. To the authors' knowledge this is the first case of mesothelioma as a secondary malignancy after BMT. |
Databáze: | OpenAIRE |
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