High biofilm production by invasive multiresistant staphylococci
| Autor: | Pedro Alves d'Azevedo, Thiago Galvão da Silva Paim, Caio Fernando de Oliveira, Keli Cristine Reiter |
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| Rok vydání: | 2011 |
| Předmět: |
Microbiology (medical)
SCCmec Biofilm General Medicine Drug resistance biochemical phenomena metabolism and nutrition Biology medicine.disease_cause Antimicrobial Pathology and Forensic Medicine Microbiology Antibiotic resistance Staphylococcus aureus medicine Immunology and Allergy Vancomycin Staphylococcus medicine.drug |
| Zdroj: | APMIS. 119:776-781 |
| ISSN: | 0903-4641 |
| DOI: | 10.1111/j.1600-0463.2011.02807.x |
| Popis: | Reiter KC, Paim TGdS, de Oliveira CF, d’Azevedo PA. High biofilm production by invasive multiresistant staphylococci. APMIS 2011; 119: 776–81. Biofilm-forming staphylococci are known for being opportunistic and invasive pathogens that cause severe disease, mostly catheter-related infections. Early detection and pathogenic strains carrying highly transferable resistance cassettes epidemiology are essential for infection spread control. Hence, this study was designed to evaluate staphylococci biofilm formation and SCCmec typing. Biofilm production and SCCmec typing were evaluated using a semi-quantitative method based on microtiter plates and a multiplex PCR for types, I–V, respectively. Blood cultures and peripheral intravenous device (IVD) staphylococci were consecutively enrolled and allocated into two different groups (invasive and colonizing) based on clinical and microbiological criteria. Seventy-four invasive and 30 colonizing isolates from distinct patients were studied. Vancomycin was the most administrated antimicrobial agent among these patient’s treatments. Biofilm formation was observed in 89% of invasive and 64% of colonizing isolates (p |
| Databáze: | OpenAIRE |
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