Cognitive Performance in Patients with Chronic Schizophrenia Across the Lifespan
| Autor: | Christina J. Herold, Marc M. Lässer, Johannes Schröder, Lena A. Schmid, Ulrich Seidl |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Cognitive flexibility Neuropsychology Cognition Audiology medicine.disease Executive functions 03 medical and health sciences 0302 clinical medicine Schizophrenia medicine Memory span 030212 general & internal medicine Effects of sleep deprivation on cognitive performance Geriatrics and Gerontology Psychiatry Psychology Gerontology Episodic memory 030217 neurology & neurosurgery |
| Zdroj: | GeroPsych. 30:35-44 |
| ISSN: | 1662-971X 1662-9647 |
| DOI: | 10.1024/1662-9647/a000164 |
| Popis: | Abstract. Chronic schizophrenia involves neuropsychological deficits that primarily strike executive functions and episodic memory. Our study investigated these deficits throughout the lifespan in patients with chronic schizophrenia and in healthy controls. Important neuropsychological functions were tested in 94 patients and 66 healthy controls, who were assigned to three age groups. Compared with the healthy controls, patients performed significantly poorer on all tests applied. Significant age effects occurred on all tests except the digit span forward, with older subjects scoring well below the younger ones. With respect to cognitive flexibility, age effects were more pronounced in the patients. These findings underline the importance of cognitive deficits in chronic schizophrenia and indicate that diminished cognitive flexibility shows age-associated differences. |
| Databáze: | OpenAIRE |
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