Biobased Technology Commercialization: The Importance of Lab to Pilot Scale-up

Autor: Robert J. Hanchar, Susanne Kleff, James P. Wynn, David Senyk, Tonya Tiedje
Rok vydání: 2016
Předmět:
Zdroj: Metabolic Engineering for Bioprocess Commercialization ISBN: 9783319419640
DOI: 10.1007/978-3-319-41966-4_6
Popis: The transition of a renewable biobased technology from lab scale (at ≤10 L) to pilot scale (≥1000 L) is a critical, though costly and intimidating, step in technology derisking. Once a process has been demonstrated at pilot scale (≥1000 L), there should be a high degree of confidence that the process can be performed successfully at commercial scale. Understanding (i) the value of pilot-scale operation; (ii) process features that can be addressed prior to pilot plant scale-up; (iii) those that have to be addressed at pilot scale; and (iv) the best approaches to pilot scale-up can make this aspect of technology derisking less intimidating, less time consuming, less expensive, and ultimately an easier sell to either management or investors.
Databáze: OpenAIRE