Effect of spacers on the activity of soluble polymer supported catalysts for the asymmetric addition of diethylzinc to aldehydes
| Autor: | Dhandapani Venkataraman, Uche K. Anyanwu |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
inorganic chemicals
chemistry.chemical_classification organic chemicals Organic Chemistry technology industry and agriculture Polymer Diethylzinc Biochemistry Catalysis chemistry.chemical_compound chemistry Drug Discovery PEG ratio Organic chemistry heterocyclic compounds Reactivity (chemistry) Enantiomer Selectivity Ethylene glycol |
| Zdroj: | Tetrahedron Letters. 44:6445-6448 |
| ISSN: | 0040-4039 |
| DOI: | 10.1016/s0040-4039(03)01588-0 |
| Popis: | A chiral Zn(II)–salen complex tethered with poly(ethylene glycol) (PEG) was synthesized. This soluble polymer-supported complex was found to catalyze the asymmetric addition of diethylzinc to a series of aromatic aldehydes in good yields and with good enantiomeric ratio (er). The PEG-supported catalyst could be recycled and reused up to three times. The reactivity and selectivity of the catalyst was dependent on the nature of the linker between the polymer and the complex. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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