Resolution of 2-methyoxy-2-(2'-thiazinyl)glycinates

Autor:	Peter B. Hitchcock, Piétrick Hudhomme, Abdelhadi Boussoufi, G. Duguay
Rok vydání:	1991
Předmět:	Resolution (mass spectrometry) Stereochemistry medicine.drug_class Organic Chemistry Diastereomer Ether Carboxamide Crystal structure Combinatorial chemistry Catalysis Inorganic Chemistry chemistry.chemical_compound chemistry Reagent X-ray crystallography medicine Physical and Theoretical Chemistry
Zdroj:	Tetrahedron: Asymmetry. 2:157-164
ISSN:	0957-4166
DOI:	10.1016/s0957-4166(00)80534-0
Popis:	The synthesis and the resolution of α-methoxy α-(2'-thiazinyl)glycinate diasteroisomers, using (S)-(-)-ethy lactate as a resolving reagent, is described. The X-ray crystal structure of a pure diastereoisomer is reported. These chirally substituted thiazines are key intermediates for multistep syntheses of 7-methoxy cephems.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::e6bbfda91baf0e912ad20b8b9597ffd8 https://doi.org/10.1016/s0957-4166(00)80534-0 Zobrazit plný text záznamu